AOP analysis workflow

How to automate/integrate AOP analysis workflow

Risk assessors face increasing demands to assess more chemicals, with greater speed and accuracy, and at the same time use fewer resources and experimental animals. New approaches in biological and computational sciences are searched to be able to generate mechanistic information that could help in meeting these challenges.

Edelweiss Connect Bioinformatician Dr. Noffisat O. Oki and  Senior Toxicologist Dr. Tatyana Doktorova took up the challenge to present the advances made by Edelweiss Connect in the field of public data usage, analysis and integration, in a webinar hosted by the American Society for Cellular and Computational Technology (ASCCT) and European Society of Toxicology In Vitro (ESTIV). They explain how computational approaches for mechanistic data integration can be used to structure available data and make its use more effective. “Our approach builds upon a previous framework for deriving in vivo toxicity responses from in vitro data and establishes an automated workflow for Adverse Outcome Pathway (AOP) hypothesis generation,” Oki explains.  

As the field of toxicology continues to evolve as a highly data-rich science, the webinar seems to have touched an important area of interest, attracting 91 participants. “Participants ranged from regulatory agencies and industry to universities all across the US and Europe,” says Tatyana. “It was nice to share what we are doing and to see such huge interest.”

You can watch the webinar here.

About Edelweiss Connect

Edelweiss Connect has developed computer software that helps combine data from many different sources and formats into a useable form for evaluation and re-use. In addition, we have developed other software programs that can use the collected data and data from in vitro tests to predict the safety of chemical compounds in the human body.

Tags

Latest Tweets

Edelweiss Connect (2 weeks ago)
RT @EU_ToxRisk: The EU-ToxRisk NAM-based Testing Commercialization Platform presented during the @EU_ToxRisk Open Symposium, Feb 12, 2020 i…
Edelweiss Connect (2 weeks ago)
RT @Biopredic_Intl: We are glad to announce the launch of the new HepaRG #logo !! Worldwide recognized and quite unique human hepatic stem…
Edelweiss Connect (3 weeks ago)
The SafeDESIgn imaging-based toxicity reporter platform for chemical safety assessment #SaferWorldbyDesign… https://t.co/7xeN1d6w6t
Edelweiss Connect (5 weeks ago)
The latest #OpenTox webinar focused on #AOPs current trends and developments, presented by Tatyana Doktorova https://t.co/ZKj5PivfiN
Edelweiss Connect (5 weeks ago)
RT @barryhardy: Tatyana Doktorova will discuss current trends and developments in Adverse Outcome Pathways as exemplified by case studies (…

Get in touch

  • Address: Edelweiss Connect GmbH
    Technology Park Basel
    Hochbergerstrasse 60C
    CH-4057 Basel / Basel-Stadt
    Switzerland

USA office

  • Address: Edelweiss Connect Inc
    Research Triangle Park NC
    800 Park Offices Dr
    Durham, NC 27709
    USA